Facebook has signed a ten-year lease deal to shift its UK headquarters from Covent Garden to Euston.
The social networking giant will move to a new 90,000 sq/ft facility across two floors of a building at 10 Brock Street, sharing the address with Twitter, Debenhams and Manchester City Football Club.
In July, Facebook revealed plans to invest $1.6bn by the end of 2013 to boost its infrastructure, while its income for the second quarter rose to $333m and generated revenue of $1.81bn.
Other firms including Yahoo and advertising groups Havas and Saatchi & Saatchi are also searching for locations beyond the boundaries of the conventional West End.
Google is also making a move from London's West End, with construction on its new £650m headquarters next to King's Cross station underway.
Upon its expected completion in 2016, Google's employees would be relocated from existing offices in Victoria and Holborn.